The sermon explores the profound nature of the New Covenant, emphasizing that knowing God is a miraculous work of divine grace rather than human effort. Drawing primarily from Hebrews 8 and John 6, it explains how the effectual call and regeneration enable sinners to move from spiritual death to a relational knowledge of Christ. This saving knowledge is defined not as intellectual assent but as an intimate, personal union with God that crushes pride and fosters humility. The preacher contrasts this divine initiative with the rebellion of the world, highlighting that salvation belongs entirely to God’s sovereign mercy. Ultimately, believers are called to respond with awe for God’s glory and pity for the lost, sharing the gospel as vessels of His grace.